Description

N6-Benzoyl-3'-o-Methyladenosine is a chemically modified nucleoside derivative, specifically an adenosine analog with protective benzoyl and methyl groups. This compound is of significant value as a key synthetic intermediate and protecting group reagent in the production of oligonucleotides and other nucleoside-based pharmaceuticals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, biotechnology, and life science sectors for advanced drug discovery and development processes.

Application

• Oligonucleotide Synthesis: Serves as a crucial protected building block (phosphoramidite) in solid-phase synthesis of DNA and RNA strands.
• Antiviral & Anticancer Prodrug Development: Used as a precursor in the research and synthesis of nucleoside analog prodrugs targeting viral replication and cancer cell proliferation.
• Biochemical Research: Acts as a substrate or inhibitor in enzymatic studies to understand adenosine-related pathways and kinase activities.
• Pharmaceutical Intermediates: A vital intermediate in the multi-step synthesis of complex therapeutic agents, including mRNA vaccine components and gene therapy products.
• Protecting Group Chemistry: The benzoyl group is utilized to protect the exocyclic amine during complex synthetic sequences, allowing for selective reactions.

Basic Information

Product Name	N6-Benzoyl-3'-o-Methyladenosine
CAS No.	85090-30-8
Molecular Formula	C18H19N5O5
Molecular Weight	385.38 g/mol
Synonyms	3'-O-Methyl-N6-benzoyladenosine; Adenosine, N6-benzoyl-3'-O-methyl-; N6-Benzoyl-3'-O-methyladenosine; 3'-O-Methyl-N(6)-benzoyladenosine; N(6)-Benzoyl-3'-O-methyladenosine; Bz-3'-OMe-Ado
EINECS	Contact for details

Quality Control

Our N6-Benzoyl-3'-o-Methyladenosine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.