Description

N4-Benzoyl-3'-o-Methylcytidine is a specifically protected nucleoside derivative, a crucial building block in oligonucleotide synthesis and pharmaceutical research. Its value lies in providing precise control over chemical reactivity, enabling the synthesis of modified RNA and DNA sequences with high fidelity. This compound is essential for researchers and manufacturers in the fields of antisense therapeutics, diagnostic probe development, and advanced biochemical research.

Application

• Solid-Phase Oligonucleotide Synthesis (SPOS): A key phosphoramidite precursor for the automated synthesis of RNA and DNA strands.
• Antisense and siRNA Drug Development: Used to create modified oligonucleotides with enhanced stability and target specificity for therapeutic applications.
• Diagnostic Probe Manufacturing: Essential for producing labeled probes used in PCR, FISH, and microarray technologies.
• Biochemical Research: Serves as a critical reagent in studying nucleic acid structure, function, and enzyme interactions.
• Pharmaceutical Intermediate: Acts as a protected intermediate in the multi-step synthesis of novel nucleoside-based antiviral or anticancer agents.

Basic Information

Product Name	N4-Benzoyl-3'-o-Methylcytidine
CAS No.	85079-03-4
Molecular Formula	C17H19N3O6
Molecular Weight	361.35 g/mol
Synonyms	3'-O-Methyl-N4-benzoylcytidine; 1-(3-O-Methyl-β-D-ribofuranosyl)-N4-benzoylcytosine; N4-Benzoyl-3'-O-methylcytidine; Bz-3'-OMe-C; N4-Benzoyl-3'-O-methylcytidine (Bz-3'-OMe-C); 3'-O-Methylcytidine, N4-benzoyl-; Cytidine, N4-benzoyl-3'-O-methyl-
EINECS	Contact for details

Quality Control

Our N4-Benzoyl-3'-o-Methylcytidine is produced under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your GMP-compliant research and production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.