Description

N6-Benzoyl-2'-o-Methyl-Adenosine is a chemically modified nucleoside derivative, specifically engineered for advanced research and pharmaceutical development. This compound is a crucial synthetic intermediate and building block in the preparation of oligonucleotides and nucleotide-based therapeutics. It is primarily utilized by researchers and manufacturers in the fields of pharmaceutical synthesis, biochemical research, and diagnostic probe development. Its structural modifications offer enhanced stability and specific reactivity, making it a valuable tool for targeted molecular design.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel antiviral and anticancer nucleotide analogs.
• Oligonucleotide Synthesis: Used in solid-phase synthesis for creating modified DNA/RNA strands with enhanced nuclease resistance.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies involving polymerases, kinases, and other nucleoside-processing enzymes.
• Probe Development: Utilized in the creation of labeled nucleotides for diagnostic assays and imaging techniques.
• Antisense Technology: A component in the development of antisense oligonucleotides for gene silencing applications.
• Academic Research: Fundamental research tool for studying nucleic acid chemistry, structure-activity relationships, and metabolic pathways.

Basic Information

Product Name	N6-Benzoyl-2'-o-Methyl-Adenosine
CAS No.	85079-00-1
Molecular Formula	C19H21N5O5
Molecular Weight	399.40 g/mol
Synonyms	2'-O-Methyl-N6-benzoyladenosine; N6-Benzoyl-2'-O-methyladenosine; 9-[(2R,3R,4R,5R)-3,4-Dihydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]-6-benzoylaminopurine; 2'-O-Methyl-N(6)-benzoyladenosine; Adenosine, N6-benzoyl-2'-O-methyl-; Bz-2'-OMe-Ado
EINECS	Contact for details

Quality Control

Our N6-Benzoyl-2'-o-Methyl-Adenosine is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for research and GMP-grade synthesis. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards, and specifications can be tailored to meet specific project requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤2.0%
Solubility	Soluble in DMSO, DMF; Slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.