Description

3-(Methoxy)Tetrafluoropropionyl Chloride is a highly reactive fluorinated acid chloride derivative, serving as a critical building block for introducing the 3-methoxytetrafluoropropionyl moiety into target molecules. Its value lies in enabling the synthesis of complex fluorinated compounds with enhanced properties such as metabolic stability, lipophilicity, and bioavailability. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for developing active ingredients and specialty polymers.

Application

• Pharmaceutical Intermediate: Key synthon for the preparation of fluorinated active pharmaceutical ingredients (APIs) and prodrugs.
• Agrochemical Synthesis: Used in creating novel fluorinated pesticides and herbicides with improved efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Building block for fluorinated components in electronic display and lighting materials.
• Polymer Modification: Imparts fluorinated characteristics to polymers, enhancing chemical resistance and surface properties.
• Peptide & Protein Labeling: Acts as a derivatization agent for analytical chemistry and biochemical research.
• Fluorinated Surfactant Precursor: Intermediate in the synthesis of specialty surfactants and surface coatings.

Basic Information

Product Name	3-(Methoxy)Tetrafluoropropionyl Chloride
CAS No.	85036-72-2
Molecular Formula	C4H3ClF4O2
Molecular Weight	194.51 g/mol
Synonyms	3-Methoxytetrafluoropropionyl Chloride; 2,2,3,3-Tetrafluoro-3-methoxypropionyl Chloride; 3-Methoxy-2,2,3,3-tetrafluoropropanoyl Chloride; α,α,β,β-Tetrafluoro-β-methoxypropionyl Chloride; Tetrafluoro-3-methoxypropionyl Chloride; 85036-72-2; Propionyl chloride, 2,2,3,3-tetrafluoro-3-methoxy-
EINECS	Contact for details

Quality Control

Our 3-(Methoxy)Tetrafluoropropionyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including GC/HPLC for purity and identity confirmation (NMR, IR) to ensure it meets stringent specifications for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, and we support compliance with relevant regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its properties as a strong acid/organic solvent, hygroscopic (moisture-sensitive), and highly volatile nature, it must be kept under an inert atmosphere (e.g., nitrogen or argon) at recommended temperatures of 2-8°C for long-term stability. Keep away from heat, sparks, open flames, and incompatible materials such as bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.