Description

(3β,5Z,7R,8α,22E)-9,10-Secoergosta-5,10(19),22-Triene-3,7,8-Triol CAS NO 84985-78-4 is a high-purity secosterol derivative, a key intermediate in the synthesis of vitamin D analogs and other biologically active steroidal compounds. Its precise stereochemistry and high purity are critical for ensuring the efficacy and safety of downstream pharmaceutical and nutraceutical products. This compound is essential for research and production in the pharmaceutical, fine chemical, and advanced life science sectors.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active vitamin D metabolites (e.g., calcitriol, tacalcitol) and other therapeutic sterols.
• Nutraceutical Research: Used in the development and study of novel vitamin D-based dietary supplements and functional ingredients.
• Biochemical Research: Serves as a reference standard and precursor in studies of steroid hormone pathways, bone metabolism, and cell differentiation.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex steroidal molecules for various industrial and academic applications.
• Cosmeceutical Development: Investigated for use in topical formulations targeting skin cell regulation and renewal.

Basic Information

Item	Details
Product Name	(3β,5Z,7R,8α,22E)-9,10-Secoergosta-5,10(19),22-Triene-3,7,8-Triol
CAS No.	84985-78-4
Molecular Formula	C₂₇H₄₄O₃
Molecular Weight	416.64 g/mol
Synonyms	9,10-Secoergosta-5,10(19),22-triene-3β,7β,8α-triol; (22E)-3β,7β,8α-Trihydroxy-9,10-seco-5,10(19),22-cholestatrien; Vitamin D3 Triol; Pre-Vitamin D3 Triol Intermediate; 3β,7β,8α-Trihydroxy-9,10-seco-5,10(19),22-cholestatrien; Secosterol Triol Derivative
EINECS	Contact for details

Quality Control

Our (3β,5Z,7R,8α,22E)-9,10-Secoergosta-5,10(19),22-Triene-3,7,8-Triol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical and research applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. For long-term storage, consider storing at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.