Description

4-Fluorophenyl 1-(2-Isothiocyanatoethyl)Piperidin-4-Yl Ketone is a specialized organic building block featuring a reactive isothiocyanate group and a fluorinated aromatic ketone moiety. This compound is of significant value in pharmaceutical research and development, serving as a key intermediate for the synthesis of novel bioactive molecules. It is primarily sought by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) targets and enzyme inhibitors.
• Chemical Biology Probe Development: The reactive isothiocyanate group enables covalent conjugation to biomolecules (e.g., proteins, peptides) for creating activity-based probes and affinity labels.
• Agrochemical Research: Used in the discovery and development of new pesticides and herbicides, leveraging the structural features for bioactivity.
• Ligand Synthesis for Medicinal Chemistry: Employed in the construction of complex piperidine-based ligands for receptor binding studies.
• Advanced Material Precursor: Can be utilized in the synthesis of functionalized polymers or organic frameworks with specific electronic or binding properties.

Basic Information

Product Name	4-Fluorophenyl 1-(2-Isothiocyanatoethyl)Piperidin-4-Yl Ketone
CAS No.	84946-22-5
Molecular Formula	C15H17FN2OS
Molecular Weight	292.37 g/mol
Synonyms	1-(2-Isothiocyanatoethyl)-4-(4-fluorobenzoyl)piperidine; 4-(4-Fluorobenzoyl)-1-(2-isothiocyanatoethyl)piperidine; 4-Fluorophenyl [1-(2-isothiocyanatoethyl)-4-piperidinyl]methanone; 84946-22-5; 1-(2-Isothiocyanatoethyl)-4-(4-fluorobenzoyl)piperidine; 4-Fluorobenzoyl-1-(2-isothiocyanatoethyl)piperidine; Ketone, 4-fluorophenyl 1-(2-isothiocyanatoethyl)-4-piperidinyl
EINECS	Contact for details

Quality Control

Our 4-Fluorophenyl 1-(2-Isothiocyanatoethyl)Piperidin-4-Yl Ketone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your research and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.