Description

p-Hydroxyphenylisopropyladenosine is a high-purity adenosine derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard in the synthesis of novel therapeutic agents targeting adenosine receptors. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery programs for cardiovascular, neurological, and inflammatory conditions. Our supply ensures consistent quality and reliable availability for your most demanding R&D and scale-up projects.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of adenosine receptor agonists and antagonists for therapeutic development.
• Biochemical Research: Used as a reference standard or ligand in receptor binding assays and pharmacological studies.
• Cardiovascular Research: Investigated for its potential role in modulating heart rate, coronary blood flow, and ischemic preconditioning.
• Neuropharmacology: Employed in studies exploring adenosine's effects on neurotransmission, neuroprotection, and sleep regulation.
• Inflammation & Immunology: Studied for its immunomodulatory and anti-inflammatory properties in various disease models.
• Process Development: Serves as a critical material for developing and optimizing scalable synthetic routes for active pharmaceutical ingredients (APIs).

Basic Information

Product Name	p-Hydroxyphenylisopropyladenosine
CAS No.	84930-20-1
Molecular Formula	C19H23N5O5
Molecular Weight	401.42 g/mol
Synonyms	PHPIA; 4-Hydroxyphenylisopropyladenosine; N6-(4-Hydroxyphenylisopropyl)adenosine; 2-[4-[(2S,3S,4R,5R)-5-(6-Aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]propan-2-yl]phenol; N6-(p-Hydroxyphenylisopropyl)adenosine; Adenosine, N6-(1-(4-hydroxyphenyl)-2-propyl)-; N6-(4-Hydroxybenzyl)adenosine derivative
EINECS	Contact for details

Quality Control

Our p-Hydroxyphenylisopropyladenosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis to ensure it meets the stringent requirements for research and development use. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.