Description

4β-Isopropylcyclohexane-1α-Carbonyl Chloride is a specialized organic intermediate featuring a reactive acid chloride functional group on a substituted cyclohexane ring. This compound matters as a critical building block for synthesizing more complex molecules, particularly in the pharmaceutical and agrochemical sectors, where its structure enables the introduction of the isopropylcyclohexyl moiety. It is needed by research chemists and process development scientists working on novel active ingredients, fine chemicals, and advanced material precursors.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators that require specific stereochemistry.
• Fine Chemical Production: Serves as a precursor for chiral ligands, catalysts, and other specialty chemicals used in asymmetric synthesis.
• Material Science Research: Employed in the development of novel polymers or liquid crystals where the cyclohexyl group imparts specific thermal or optical properties.
• Peptide & Protein Modification: The reactive carbonyl chloride group can be used to acylate amino groups, facilitating the conjugation of the isopropylcyclohexyl fragment to biomolecules.
• Fragrance & Flavor Chemistry: Potential intermediate for creating synthetic musks or other complex aroma chemicals with unique stability profiles.

Basic Information

Product Name	4β-Isopropylcyclohexane-1α-Carbonyl Chloride
CAS No.	84855-54-9
Molecular Formula	C10H17ClO
Molecular Weight	188.69 g/mol
Synonyms	trans-4-Isopropylcyclohexanecarbonyl Chloride; (1R,4S)-4-Isopropylcyclohexanecarbonyl Chloride; 4-Isopropylcyclohexanecarboxylic Acid Chloride; 1α-Carbonyl Chloride-4β-isopropylcyclohexane; 4β-Isopropyl-1α-cyclohexanecarbonyl Chloride; 4-trans-Isopropylcyclohexanecarbonyl Chloride; p-Isopropylcyclohexanecarbonyl Chloride
EINECS	Contact for details

Quality Control

Our 4β-Isopropylcyclohexane-1α-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing specific results for purity, water content, and other critical parameters are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic and moisture-sensitive nature, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.