Description

(3B,5B,12B)- 3,12 Dihydroxy- Cholan-24-Oic Acid is a high-purity bile acid derivative, a critical intermediate in the synthesis of pharmaceutical actives and fine chemicals. Its precise stereochemistry and functional groups make it a valuable building block for research and production in advanced therapeutic areas. This compound is essential for manufacturers and R&D laboratories focused on developing innovative pharmaceutical compounds and biochemical reagents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of ursodeoxycholic acid (UDCA) and other therapeutic bile acids.
• Biochemical Research: Used as a standard or reagent in metabolic pathway studies, hepatology research, and enzyme interaction assays.
• Fine Chemical Synthesis: Serves as a versatile starting material for the preparation of steroidal compounds with modified biological activity.
• Reference Standard: Employed in analytical laboratories for method development, validation, and quality control testing of related substances.
• API Development: Investigated in the development of new Active Pharmaceutical Ingredients (APIs) targeting liver and metabolic disorders.

Basic Information

Product Name	(3B,5B,12B)- 3,12 Dihydroxy- Cholan-24-Oic Acid
CAS No.	84848-09-9
Molecular Formula	C24H40O4
Molecular Weight	392.57 g/mol
Synonyms	3α,12α-Dihydroxy-5β-cholan-24-oic Acid; 3α,12α-Dihydroxy-5β-cholanic Acid; 3α,12α-Dihydroxy-5β-cholanoic Acid; 5β-Cholan-24-oic acid-3α,12α-diol; Allocholic Acid; 3α,12α-Dihydroxy-5β-cholanate; (3α,5β,12α)-3,12-Dihydroxycholan-24-oic Acid
EINECS	Contact for details

Quality Control

Our (3B,5B,12B)- 3,12 Dihydroxy- Cholan-24-Oic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical and research applications. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Specific Rotation	Contact for details
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.