Description

Itraconazole is a potent, broad-spectrum triazole antifungal agent widely used in pharmaceutical formulations. Its primary value lies in its efficacy against a wide range of fungal pathogens, including Aspergillus, Candida, and dermatophytes, making it a cornerstone in systemic antifungal therapy. This high-purity active pharmaceutical ingredient (API) is essential for manufacturers in the pharmaceutical industry developing oral capsules, solutions, and other dosage forms for the treatment of various fungal infections.

Application

• Pharmaceutical API: Primary use as the active ingredient in antifungal medications for systemic and topical treatments.
• Oral Formulations: Manufacture of capsules and oral solutions for treating systemic fungal infections like aspergillosis, blastomycosis, and histoplasmosis.
• Topical Preparations: Used in creams, ointments, and gels for dermatological conditions such as onychomycosis (nail fungus) and tinea corporis (ringworm).
• Veterinary Medicine: Formulation of antifungal treatments for companion animals and livestock.
• Research & Development: Serves as a reference standard and key intermediate in pharmacological and microbiological research.
• Hospital Compounding: Used in specialized pharmacy compounding for patient-specific antifungal therapies.

Basic Information

Product Name	Itraconazole
CAS No.	84625-61-6
Molecular Formula	C35H38Cl2N8O4
Molecular Weight	705.64 g/mol
Synonyms	4-[4-[4-[4-[[(2R*,4S*)-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-2,4-dihydro-2-[(1S*,2S*)-1-methyl-2-pentyl]-3H-1,2,4-triazol-3-one; R 51211; Sporanox; Oriconazole; Itrizole; Itrasys; Itranax; Sempera
EINECS	Contact for details

Quality Control

Our Itraconazole CAS NO 84625-61-6 is manufactured under strict quality management systems. We ensure compliance with major pharmacopoeial standards, including USP (United States Pharmacopeia) and EP (European Pharmacopoeia) monographs. Every batch undergoes rigorous analytical testing for identity, purity, and potency. Comprehensive Certificates of Analysis (COA) documenting all test results are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability and efficacy.

Specification

Item	Specification
Appearance	White or almost white powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Microbial Limits	Conforms to EP/USP

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.