Description

5'-(6-Aminopurin-9-Yl)-5'-Deoxyribofuranose 1',2'-Cyclic Monophosphate is a specialized nucleotide derivative, a key intermediate in the synthesis of cyclic nucleotide analogs and other biologically active compounds. Its precise molecular structure makes it a critical building block for advanced research and development in life sciences. This high-purity biochemical is essential for pharmaceutical R&D, academic research, and the development of novel therapeutic agents targeting cellular signaling pathways.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel adenosine receptor agonists, antagonists, and other nucleotide-based therapeutics.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving phosphodiesterases and kinases, to investigate cyclic nucleotide signaling.
• Probe & Diagnostic Development: Serves as a core structure for developing labeled probes (e.g., fluorescent, radioactive) for cellular imaging and diagnostic assays.
• Nucleotide Chemistry: A valuable starting material for organic and medicinal chemists exploring modified nucleosides and nucleotides with enhanced stability or biological activity.
• Cell Signaling Studies: Employed in research to modulate intracellular second messenger pathways, helping to elucidate mechanisms in physiology and disease states.

Basic Information

Product Name	5'-(6-Aminopurin-9-Yl)-5'-Deoxyribofuranose 1',2'-Cyclic Monophosphate
CAS No.	84498-18-0
Molecular Formula	C10H12N5O6P
Molecular Weight	329.21 g/mol
Synonyms	9-(5-Deoxy-β-D-ribofuranosyl)adenine 3',5'-Cyclic Monophosphate; 5'-Deoxyadenosine 3',5'-Cyclic Monophosphate; 5'-Deoxy-cAMP; 5'-Deoxyadenosine Cyclic 3',5'-Monophosphate; 5'-Deoxy-3',5'-cAMP; 5'-Deoxy Cyclic AMP; 5'-Deoxy-cAMP; 5'-Deoxyadenosine 3',5'-cyclic phosphate
EINECS	Contact for details

Quality Control

Our 5'-(6-Aminopurin-9-Yl)-5'-Deoxyribofuranose 1',2'-Cyclic Monophosphate is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture. A Certificate of Analysis (COA) detailing all specifications is provided to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.