Description

3'-Amino-2',3'-Dideoxycytidine is a modified nucleoside analog of significant interest in pharmaceutical research and development. This compound serves as a critical building block and intermediate for synthesizing novel antiviral and anticancer agents, particularly nucleoside reverse transcriptase inhibitors. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in the development of therapeutic nucleotides. The precise chemical structure of this intermediate allows for targeted modifications in drug discovery programs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor for the development of novel antiviral drugs, including potential treatments for HIV and hepatitis.
• Anticancer Agent Research: Used in the synthesis and screening of nucleoside analogs designed to inhibit cancer cell proliferation.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies to understand nucleotide metabolism and polymerase function.
• Prodrug Development: Serves as a base molecule for creating prodrugs with improved bioavailability and targeted delivery.
• Antisense Oligonucleotide Synthesis: Can be incorporated into oligonucleotide chains for genetic research and therapeutic applications.
• Reference Standard: Used as a high-purity analytical standard in quality control and regulatory testing for pharmaceutical products.

Basic Information

Product Name	3'-Amino-2',3'-Dideoxycytidine
CAS No.	84472-90-2
Molecular Formula	C9H14N4O3
Molecular Weight	226.23 g/mol
Synonyms	3'-Amino-2',3'-dideoxycytidine; 2',3'-Dideoxy-3'-aminocytidine; 3'-Amino-ddC; 4-Amino-1-((2R,5S)-5-(aminomethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one; NSC 614391; 3'-Amino-2',3'-dideoxycytidine (3'-amino-ddC); 3'-Amino-2',3'-dideoxycytidine, 3'-Amino-DDC
EINECS	Contact for details

Quality Control

Our 3'-Amino-2',3'-Dideoxycytidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Our quality commitment supports applications requiring high-purity biochemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.