Description

3'-Azido-2'-Deoxy-D-Cytidine is a modified nucleoside analog of deoxycytidine, featuring an azido group at the 3' position of the sugar moiety. This specific structural modification makes it a valuable intermediate and building block in the synthesis of novel antiviral and anticancer agents, particularly in the development of nucleoside reverse transcriptase inhibitors (NRTIs). It is essential for pharmaceutical R&D, medicinal chemistry, and academic research focused on probing nucleic acid metabolism and developing targeted therapies. The compound is supplied with high purity to meet the stringent requirements of advanced biochemical applications.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of experimental antiviral drugs and nucleoside-based therapeutics.
• Medicinal Chemistry Research: Used as a building block for structure-activity relationship (SAR) studies to develop new bioactive compounds.
• Biochemical Probe: Employed in studies investigating DNA/RNA synthesis inhibition and the mechanisms of nucleoside analogs.
• Antiviral Agent Development: Serves as a key intermediate for potential inhibitors targeting viral polymerases.
• Academic & Institutional Research: Utilized in university and laboratory settings for fundamental research in biochemistry and molecular biology.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations for custom synthesis projects.

Basic Information

Product Name	3'-Azido-2'-Deoxy-D-Cytidine
CAS No.	84472-89-9
Molecular Formula	C9H12N6O4
Molecular Weight	268.23 g/mol
Synonyms	3'-Azido-3'-deoxycytidine; 3'-Azido-2',3'-dideoxycytidine; 3'-N3-2'-dC; Azidodideoxycytidine; 1-(3-Azido-2,3-dideoxy-β-D-erythro-pentofuranosyl)cytosine; 3'-Azido-2',3'-dideoxycytidine; NSC 675186; 3'-Azido-ddC
EINECS	Contact for details

Quality Control

Our 3'-Azido-2'-Deoxy-D-Cytidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture content. We provide a Certificate of Analysis (COA) with every shipment, detailing all specifications and test results to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.