Description

3'-Azido-2',3'-Dideoxyuridine is a chemically modified nucleoside analog of significant interest in pharmaceutical research and development. This compound serves as a critical building block and intermediate in the synthesis of novel antiviral agents and other therapeutic molecules. It is primarily utilized by research institutions, pharmaceutical companies, and biotechnology firms engaged in drug discovery programs targeting viral diseases and exploring nucleoside-based therapeutics.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of nucleoside reverse transcriptase inhibitors (NRTIs) and other antiviral drugs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to understand viral replication mechanisms, particularly for HIV and other retroviruses.
• Pro-drug Synthesis: Serves as a core structure for designing and synthesizing novel pro-drug candidates with improved bioavailability and targeted delivery.
• Antiviral Agent Development: Investigated for its direct antiviral activity and as a model compound for structure-activity relationship (SAR) studies.
• Labeled Compound Production: Acts as a starting material for the synthesis of isotopically labeled (e.g., 13C, 15N) analogs for metabolic and pharmacokinetic studies.
• Academic Research: Employed in university and institutional labs for fundamental studies in medicinal chemistry and nucleic acid chemistry.

Basic Information

Product Name	3'-Azido-2',3'-Dideoxyuridine
CAS No.	84472-85-5
Molecular Formula	C9H11N5O5
Molecular Weight	269.22 g/mol
Synonyms	3'-Azido-3'-deoxythymidine (AZT) analog; 3'-Azido-2',3'-dideoxyuridine; Azidodideoxyuridine; 1-[(2R,5S)-5-Azido-2,5-dihydro-2-furanyl]-2,4(1H,3H)-pyrimidinedione; CS-824; NSC 684164; Uridine, 3'-azido-2',3'-dideoxy-
EINECS	Contact for details

Quality Control

Our 3'-Azido-2',3'-Dideoxyuridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Custom purity grades and analytical packages are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.