Description

(22R)-5β,6β-Epoxy-4β,12β,22,27-Tetrahydroxy-1-Oxo-5β-Ergosta-2,24-Dien-26-Oic Acid δ-Lactone is a highly functionalized ergostane-type steroidal lactone, valued for its complex molecular architecture and biological relevance. This compound serves as a critical advanced intermediate or reference standard in pharmaceutical research and development, particularly for studying sterol biosynthesis and metabolic pathways. It is essential for R&D teams in the pharmaceutical, biotechnology, and fine chemical synthesis sectors seeking high-purity, structurally defined bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor or building block for the development of novel steroidal drugs and bioactive compounds.
• Biochemical Research: Used as a reference standard or probe in studies of enzyme inhibition, sterol metabolism, and signal transduction pathways.
• Natural Product Synthesis: Acts as a starting material or intermediate in the total synthesis or semi-synthesis of complex natural products with ergostane skeletons.
• Analytical Standard: Provides a high-purity calibrant for analytical methods such as HPLC, LC-MS, and NMR in quality control and method development laboratories.
• Academic Research: Utilized in university and institutional labs for investigating the structure-activity relationships (SAR) of polyhydroxylated sterols.

Basic Information

Product Name	(22R)-5β,6β-Epoxy-4β,12β,22,27-Tetrahydroxy-1-Oxo-5β-Ergosta-2,24-Dien-26-Oic Acid δ-Lactone
CAS No.	84461-54-1
Molecular Formula	C₂₈H₃₈O₈
Molecular Weight	502.60 g/mol
Synonyms	5β,6β-Epoxyergosta-2,24-diene-1,4,12,22,27-pentaol-26-oic acid 26,22-lactone; (22R)-5β,6β-Epoxy-4β,12β,22,27-tetrahydroxy-1-oxoergosta-2,24-dien-26-oic acid δ-lactone; 22R-Epoxy-tetrahydroxy-oxoergostadienoic acid lactone; NSC 339585; Ergostane lactone derivative; Polyhydroxylated ergostane lactone
EINECS	Contact for details

Quality Control

Every batch of our (22R)-5β,6β-Epoxy-4β,12β,22,27-Tetrahydroxy-1-Oxo-5β-Ergosta-2,24-Dien-26-Oic Acid δ-Lactone is manufactured and tested under a strict quality management system. We provide comprehensive analytical documentation, including a Certificate of Analysis (COA) detailing purity, identity, and impurity profiles as determined by HPLC, NMR, and MS. Our quality commitment ensures the material is suitable for demanding research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.