Description

(22R)-5β,6β-Epoxy-4β,15β,22,27-Tetrahydroxy-1-Oxo-5β-Ergosta-2,24-Dien-26-Oic Acid δ-Lactone is a highly functionalized ergostane-type steroidal lactone, representing a key advanced intermediate in the synthesis of complex bioactive molecules. Its intricate polycyclic structure with multiple oxygenated functional groups makes it a valuable scaffold for pharmaceutical research and development. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and synthesis of novel steroidal drugs and biochemical probes.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of complex steroidal active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or precursor in metabolic pathway studies and enzyme inhibition assays related to sterol biosynthesis.
• Medicinal Chemistry: Provides a versatile core structure for the design and development of new drug candidates targeting various receptors.
• Academic Research: Employed in universities and research institutes for studying organic synthesis methodologies, particularly oxidation and lactonization reactions.
• Natural Product Synthesis: Acts as a synthetic target or intermediate in the total or semi-synthesis of complex natural products with ergostane skeletons.

Basic Information

Product Name	(22R)-5β,6β-Epoxy-4β,15β,22,27-Tetrahydroxy-1-Oxo-5β-Ergosta-2,24-Dien-26-Oic Acid δ-Lactone
CAS No.	84461-53-0
Molecular Formula	C₂₈H₃₈O₈
Molecular Weight	502.60 g/mol
Synonyms	22R-Hydroxywithanolide E; (22R)-5β,6β-Epoxy-4β,15β,22,27-tetrahydroxy-1-oxoergosta-2,24-dien-26-oic acid δ-lactone; 22R-Hydroxy-5β,6β-epoxy-4β,15β,22,27-tetrahydroxy-1-oxoergosta-2,24-dien-26-oic acid δ-lactone; Withanolide E derivative; Ergosta-2,24-dien-26-oic acid lactone derivative
EINECS	Contact for details

Quality Control

Our (22R)-5β,6β-Epoxy-4β,15β,22,27-Tetrahydroxy-1-Oxo-5β-Ergosta-2,24-Dien-26-Oic Acid δ-Lactone is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and specific tests for residual solvents and related substances. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.