Description

5-(Aminomethyl)-3-[4-[2-[3-(Trifluoromethyl)Phenyl]Ethyl]Phenyl]Oxazolidin-2-One Hydrochloride is a high-purity, non-racemic pharmaceutical intermediate of significant commercial and research interest. Its value lies in its role as a key chiral building block for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of novel therapeutics. This compound is essential for pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of advanced drug candidates, where precise stereochemistry and reliable supply are critical.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel oxazolidinone-based antibiotic candidates and other therapeutic agents.
• API Development: Serves as a key building block in the research and process development of new Active Pharmaceutical Ingredients (APIs).
• Organic Synthesis: Used in advanced organic chemistry for constructing complex molecules with defined stereocenters.
• Medicinal Chemistry Research: A valuable compound for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Fine Chemical Manufacturing: Employed in the multi-step synthesis of high-value specialty chemicals for the life sciences industry.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process scale-up services.

Basic Information

Product Name	5-(Aminomethyl)-3-[4-[2-[3-(Trifluoromethyl)Phenyl]Ethyl]Phenyl]Oxazolidin-2-One Hydrochloride
CAS No.	84459-95-0
Molecular Formula	C19H18F3N2O2·HCl
Molecular Weight	408.81 g/mol
Synonyms	5-(Aminomethyl)-3-[4-[2-[3-(trifluoromethyl)phenyl]ethyl]phenyl]-2-oxazolidinone hydrochloride; (R)- or (S)- enantiomer forms (specify); Oxazolidinone derivative hydrochloride; 84459-95-0; Pharmaceutical intermediate 84459-95-0; Trifluoromethylphenyl oxazolidinone HCl; Non-racemic oxazolidinone building block.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and purity for sensitive pharmaceutical applications. Certificates of Analysis (COA) are provided with each shipment, detailing key parameters such as chiral purity, chemical purity, and impurity profiles. Quality is assured through analytical methods including HPLC, NMR, and chiral analysis. We operate under a quality management system designed to meet the expectations of GMP-oriented customers.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee (enantiomer specified)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.