Description

Bicyclo[4.1.0]Heptane-7-Carbonyl Chloride, 7-Chloro- (9Ci) is a highly reactive and versatile bicyclic acid chloride derivative. This compound is a critical synthetic intermediate valued for its strained ring system and functional handles, enabling complex molecular construction. It is primarily sought after by R&D chemists and process development teams in the pharmaceutical and advanced materials sectors for constructing novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting complex, three-dimensional molecular architectures.
• Agrochemical Synthesis: Used in the research and development of new generation pesticides and herbicides, where its bicyclic core can impart unique biological activity and stability.
• Advanced Material Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers, resins, and high-performance materials with tailored thermal or mechanical properties.
• Organic Synthesis Reagent: An essential reagent for introducing the bicyclo[4.1.0]heptane scaffold and carbonyl functionality into target molecules via acylations and further derivatizations.
• Ligand and Catalyst Development: Employed in the creation of novel chiral ligands or organocatalysts for asymmetric synthesis applications.
• Chemical Biology Probe Synthesis: Used to create molecular probes for studying biological pathways and protein interactions due to its reactive handle and potential for bioconjugation.

Basic Information

Product Name	Bicyclo[4.1.0]Heptane-7-Carbonyl Chloride, 7-Chloro- (9Ci)
CAS No.	84322-59-8
Molecular Formula	C8H8Cl2O
Molecular Weight	191.06 g/mol
Synonyms	7-Chlorobicyclo[4.1.0]heptane-7-carbonyl chloride; 7-Chloro-7-bicyclo[4.1.0]heptanecarbonyl chloride; 1-Chloro-4-(chlorocarbonyl)bicyclo[4.1.0]heptane; Bicyclo[4.1.0]heptane-7-carbonyl chloride, 7-chloro-; 7-Chloronorcarane-7-carbonyl chloride
EINECS	Contact for details

Quality Control

Every batch of Bicyclo[4.1.0]Heptane-7-Carbonyl Chloride, 7-Chloro- (9Ci) is manufactured and analyzed under strict quality management protocols. We provide comprehensive analytical data to ensure the material meets the precise requirements of your synthetic application. A detailed Certificate of Analysis (COA) confirming identity, purity, and impurity profile is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.