Description

4-Hydroxy-1-Methyl-n-(4-Methyl-1,3-Thiazol-2-Yl)-2-Oxo-1,2-Dihydroquinoline-3-Carboxamide is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular design. It is primarily sought by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in drug discovery and development programs.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the research and synthesis of new chemical entities (NCEs) and potential drug candidates.
• API Synthesis: Used in the development and scale-up production of active pharmaceutical ingredients, especially those with quinoline and thiazole pharmacophores.
• Medicinal Chemistry Research: A valuable scaffold for structure-activity relationship (SAR) studies and lead optimization in academic and industrial R&D labs.
• Biochemical Research: Employed in the study of enzyme inhibition and receptor binding assays due to its specific molecular architecture.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	4-Hydroxy-1-Methyl-n-(4-Methyl-1,3-Thiazol-2-Yl)-2-Oxo-1,2-Dihydroquinoline-3-Carboxamide
CAS No.	84088-59-5
Molecular Formula	C₁₆H₁₅N₃O₃S
Molecular Weight	329.37 g/mol
Synonyms	4-Hydroxy-1-methyl-N-(4-methyl-1,3-thiazol-2-yl)-2-oxo-1,2-dihydroquinoline-3-carboxamide; 4-Hydroxy-1-methyl-2-oxo-N-(4-methylthiazol-2-yl)-1,2-dihydroquinoline-3-carboxamide; Quinoline-3-carboxamide, 1,2-dihydro-4-hydroxy-1-methyl-2-oxo-N-(4-methyl-2-thiazolyl)-; 84088-59-5; UNII-8B0Q5S8K4I; 8B0Q5S8K4I
EINECS	Contact for details

Quality Control

Our production of 4-Hydroxy-1-Methyl-n-(4-Methyl-1,3-Thiazol-2-Yl)-2-Oxo-1,2-Dihydroquinoline-3-Carboxamide adheres to stringent quality management systems. The material is manufactured and controlled to meet high-purity standards suitable for pharmaceutical research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each batch to ensure traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.