Description

Ropivacaine is a long-acting amide-type local anesthetic agent, known for its favorable safety profile and reduced cardiotoxicity compared to similar compounds. It is a critical active pharmaceutical ingredient (API) used in the formulation of injectable solutions for regional anesthesia and acute pain management. This high-purity compound is essential for pharmaceutical manufacturers and research institutions developing advanced analgesic and anesthetic products.

Application

• Pharmaceutical API: Primary use as the active ingredient in injectable anesthetic solutions for surgical and post-operative pain control.
• Regional Anesthesia: Formulation into solutions for nerve blocks, epidural anesthesia, and peripheral nerve blockade.
• Acute Pain Management: Development of controlled-release formulations for managing post-surgical and trauma-related pain.
• Clinical Research: Used as a reference standard and investigational material in pharmacological and toxicological studies.
• Veterinary Medicine: Application in veterinary surgical procedures requiring local or regional anesthesia.
• Analgesic Preparations: Component in specialized pain relief gels or patches under development.

Basic Information

Product Name	Ropivacaine
CAS No.	84057-95-4
Molecular Formula	C17H26N2O
Molecular Weight	274.40 g/mol
Synonyms	(S)-(-)-1-Propyl-2',6'-pipecoloxylidide; (S)-Ropivacaine; Naropin (Trade Name); LEA 103; S-(-)-Ropivacaine; 1-Propyl-2',6'-pipecoloxylidide; (2S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide
EINECS	Contact for details

Quality Control

Our Ropivacaine is manufactured under strict quality management systems. Each batch is tested to meet high-purity standards suitable for pharmaceutical applications, with specifications aligning with major pharmacopoeial guidelines. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing results for identity, purity, assay, and impurity profiles to ensure supply reliability and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 99.0%
Specific Rotation	-80° to -85° (c=1 in methanol)
Related Substances (HPLC)	Individual impurity ≤ 0.1%; Total impurities ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 10 ppm
Sulfated Ash	≤ 0.1%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.