Description

Tetracaine Hydrochloride CAS NO 136-47-0 is a potent local anesthetic of the ester type, widely recognized for its rapid onset and prolonged duration of action. This high-purity active pharmaceutical ingredient (API) is critical for ensuring the efficacy and safety of topical and injectable anesthetic formulations. It is an essential component for manufacturers in the pharmaceutical, ophthalmic, and research sectors requiring reliable, high-grade anesthetic agents for medical and diagnostic procedures.

Application

• Pharmaceutical Manufacturing: As a key API in the production of topical anesthetic creams, ointments, gels, and solutions for surface anesthesia.
• Ophthalmic Solutions: Used in eye drops and surgical preparations for corneal anesthesia during diagnostic procedures and minor ocular surgeries.
• Injectable Anesthetics: Formulated for spinal and regional anesthesia, providing effective nerve block for surgical and therapeutic interventions.
• Dental Anesthetics: Incorporated into gels and solutions for mucosal surface anesthesia prior to dental procedures.
• Veterinary Medicine: Employed in anesthetic preparations for topical and minor surgical use in animals.
• Research & Development: Serves as a reference standard and biochemical tool in pharmacological studies of sodium channel blockers and local anesthetic mechanisms.
• Diagnostic Aid: Used to anesthetize mucous membranes for endoscopic examinations and intubation.

Basic Information

Product Name	Tetracaine Hydrochloride
CAS No.	136-47-0
Molecular Formula	C15H24N2O2 • HCl
Molecular Weight	300.83 g/mol
Synonyms	2-(Dimethylamino)ethyl 4-(butylamino)benzoate hydrochloride; Amethocaine Hydrochloride; Pantocaine Hydrochloride; Anethaine; Dicaine; Pontocaine Hydrochloride; Tetracainium Chloride; Benzoic acid, 4-(butylamino)-, 2-(dimethylamino)ethyl ester, hydrochloride
EINECS	205-235-8

Quality Control

Our Tetracaine Hydrochloride is manufactured under strict quality management systems, with specifications designed to meet or exceed USP, EP, and BP pharmacopeial standards. Each batch undergoes comprehensive analytical testing, including identity, purity, and impurity profile verification. A Certificate of Analysis (COA) documenting all test results is provided to ensure full traceability and compliance for our pharmaceutical partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term stability, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White or almost white, crystalline powder
Identification (IR)	Conforms to standard
Identification (Chloride)	Conforms to standard
Assay (HPLC)	98.5% - 101.0% (on dried basis)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 1.0% Any individual impurity ≤ 0.5%
pH (1% Solution)	4.5 - 6.0

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.