Description

Ropivacaine Hydrochloride is a long-acting local anesthetic of the amide type, widely recognized for its favorable safety profile and reduced cardiotoxicity compared to similar agents. This high-purity active pharmaceutical ingredient (API) is essential for the formulation of injectable solutions used in regional anesthesia and postoperative pain management. It is a critical component for pharmaceutical manufacturers and research institutions developing advanced analgesic products.

Application

• Primary API in the manufacture of injectable local anesthetic solutions for surgical and medical procedures.
• Key ingredient for nerve block formulations, including epidural, spinal, and peripheral nerve blocks.
• Used in the development of controlled-release or extended-release pain management pharmaceutical products.
• Essential raw material for compounding pharmacies specializing in hospital and clinical anesthetic preparations.
• Reference standard and building block in pharmaceutical research and development for novel anesthetic agents.
• Starting material for the synthesis of related amide-type local anesthetic derivatives in chemical research.

Basic Information

Item	Details
Product Name	Ropivacaine Hydrochloride
CAS No.	98717-15-8
Molecular Formula	C17H26N2O • HCl
Molecular Weight	310.86 g/mol (as hydrochloride salt)
Synonyms	(S)-(-)-1-Propyl-2',6'-pipecoloxylidide Hydrochloride; (S)-Ropivacaine HCl; Naropin (brand name); LEAF-8520; Ropivacaine Monohydrochloride; (2S)-N-(2,6-Dimethylphenyl)-1-propylpiperidine-2-carboxamide hydrochloride
EINECS	Contact for details

Quality Control

Our Ropivacaine Hydrochloride is manufactured under strict quality systems to meet the exacting standards of the pharmaceutical industry. Each batch is subjected to comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure compliance with relevant pharmacopeial monographs (e.g., USP, EP). A Certificate of Analysis (COA) documenting all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to almost white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Specific Rotation	-80.0° to -90.0° (c=1 in methanol)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.