Description

Cyclomethycaine is a potent local anesthetic agent belonging to the ester class of anesthetics. This compound is valued for its effective surface numbing properties, providing rapid onset of action for targeted relief. It is primarily utilized in the pharmaceutical and medical industries for the formulation of topical preparations designed to alleviate pain and discomfort associated with minor skin irritations, hemorrhoids, and certain medical procedures.

Application

• Topical Anesthetic Formulations: A key ingredient in creams, ointments, gels, and sprays for temporary relief of pain and itching.
• Hemorrhoidal Preparations: Used in over-the-counter and prescription products to reduce pain, swelling, and itching associated with hemorrhoids.
• Dermatological Products: Incorporated into treatments for minor burns, sunburn, insect bites, and other superficial skin conditions.
• Medical Device Coatings: Applied on certain catheters or probes to provide localized anesthesia during insertion.
• Veterinary Medicine: Employed in topical preparations for animals to manage pain from minor wounds or surgical sites.
• Research & Development: Serves as a reference standard and active pharmaceutical ingredient (API) in pharmacological studies and new product development.

Basic Information

Product Name	Cyclomethycaine
CAS No.	139-62-8
Molecular Formula	C20H31NO3
Molecular Weight	333.47 g/mol
Synonyms	Cyclomethycaine; 3-(2-Methylpiperidino)propyl 4-cyclohexyloxybenzoate; Cyclomethyacaine; Surfacaine; Topocaine; 4-Cyclohexyloxybenzoic Acid 3-(2-Methyl-1-piperidyl)propyl Ester; 1-Piperidinepropanoic Acid, 2-Methyl-, 4-Cyclohexyloxybenzyl Ester
EINECS	205-374-9

Quality Control

Our Cyclomethycaine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and the absence of critical impurities. We support compliance with cGMP, ICH Q7, and relevant pharmacopoeial guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.