Description

5-Iodo-5'-o-(2-Methylpropionyl)-2'-Deoxyuridine is a chemically modified nucleoside analog, a key intermediate in the synthesis of advanced antiviral and anticancer compounds. Its value lies in its role as a versatile building block for creating prodrugs and targeted therapeutic agents, particularly in nucleoside-based drug development. This high-purity intermediate is essential for pharmaceutical R&D laboratories and manufacturers focused on antiviral therapies, oncology research, and nucleotide chemistry.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel antiviral and anticancer nucleoside analogs.
• Antiviral Prodrug Development: Used in research and production of prodrugs targeting viruses such as herpes simplex virus (HSV) and cytomegalovirus (CMV).
• Oncology Research: Serves as a precursor in the development of chemotherapeutic agents that target DNA synthesis in cancer cells.
• Biochemical Research: Employed in studies of enzyme kinetics, DNA/RNA interactions, and nucleotide metabolism.
• Radiopharmaceuticals: Potential precursor for iodine-labeled compounds used in diagnostic imaging and targeted radiotherapy.
• Nucleotide Chemistry: Used in academic and industrial research to explore new modifications of nucleosides for enhanced biological activity.

Basic Information

Product Name	5-Iodo-5'-o-(2-Methylpropionyl)-2'-Deoxyuridine
CAS No.	84043-27-6
Molecular Formula	C13H17IN2O6
Molecular Weight	424.19 g/mol
Synonyms	5-Iodo-5'-O-isobutyryl-2'-deoxyuridine; 5-Iodo-2'-deoxy-5'-O-(2-methyl-1-oxopropyl)uridine; 5-Iododeoxyuridine 5'-isobutyrate; 5'-O-Isobutyryl-5-iodo-2'-deoxyuridine; IDU 5'-isobutyrate; 5-Iodo-2'-deoxyuridine 5'-(2-methylpropanoate); 84043-27-6; 5-Iodo-5'-O-(2-methylpropionyl)-2'-deoxyuridine
EINECS	Contact for details

Quality Control

Our 5-Iodo-5'-o-(2-Methylpropionyl)-2'-Deoxyuridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical research. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a low-humidity environment. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.