Description

5-Iodo-5'-o-Propionyl-2'-Deoxyuridine is a chemically modified nucleoside derivative, primarily utilized as a critical intermediate in advanced pharmaceutical synthesis and biochemical research. This compound is valued for its role in the development of antiviral and anticancer agents, particularly in the synthesis of modified nucleic acids and prodrugs. It is essential for research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on nucleoside chemistry and targeted therapeutic development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used in studies investigating DNA/RNA metabolism, enzyme mechanisms, and as a substrate for various kinases and polymerases.
• Prodrug Development: Serves as a precursor in creating prodrugs designed for improved cellular uptake and targeted drug delivery.
• Antiviral Agent Synthesis: Integral to the research and development pipeline for compounds targeting viral replication.
• Labeling and Tracing: Potential use in radiolabeling (with I-125/I-131) for diagnostic imaging or metabolic pathway tracing studies.
• Academic & Industrial R&D: Employed in organic synthesis laboratories for method development and exploring new chemical entities in medicinal chemistry.

Basic Information

Product Name	5-Iodo-5'-o-Propionyl-2'-Deoxyuridine
CAS No.	84043-25-4
Molecular Formula	C12H15IN2O6
Molecular Weight	410.16 g/mol
Synonyms	5-Iodo-5'-O-propionyl-2'-deoxyuridine; 2'-Deoxy-5-iodouridine 5'-propionate; 5-Iodo-2'-deoxyuridine 5'-propanoate; 5-Iododeoxyuridine 5'-O-propionate; IDU 5'-Propionate; 5-Iodo-5'-O-(1-oxopropoxy)-2'-deoxyuridine; 5-Iodouridine 2'-deoxy-5'-propionate; 84043-25-4
EINECS	Contact for details

Quality Control

Our 5-Iodo-5'-o-Propionyl-2'-Deoxyuridine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent control of residual solvents and impurities. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.