Description

1,3-Dimethylbutyl Chloroformate is a specialized alkyl chloroformate ester used as a versatile reagent in organic synthesis. Its primary value lies in its role as a protecting and activating agent, particularly for the introduction of the 1,3-dimethylbutyloxycarbonyl group. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, where it is employed in peptide synthesis and the production of advanced intermediates.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for introducing protecting groups in the multi-step synthesis of active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Used as a coupling agent or for the temporary protection of amine functionalities during solid-phase and solution-phase peptide synthesis.
• Fine Chemical Production: Employed in the manufacture of complex organic molecules, including agrochemicals and specialty polymers.
• Carbamate Formation: Effective reagent for the synthesis of carbamate derivatives, which are important in various medicinal and material science applications.
• Chemical Research & Development: A valuable tool for organic chemists in academia and R&D for exploring new synthetic methodologies.

Basic Information

Product Name	1,3-Dimethylbutyl Chloroformate
CAS No.	84000-72-6
Molecular Formula	C7H13ClO2
Molecular Weight	164.63 g/mol
Synonyms	Chloroformic Acid 1,3-Dimethylbutyl Ester; 1,3-Dimethylbutyl Carbonochloridate; 4-Methylpentyl Chloroformate; Isohexyl Chloroformate; (1,3-Dimethylbutoxy)carbonyl Chloride; NSC 163045
EINECS	Contact for details

Quality Control

Our 1,3-Dimethylbutyl Chloroformate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including assay by GC or HPLC and identification by FT-IR, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at recommended temperatures (typically 2-8°C or as specified). Due to its hygroscopic and highly volatile nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) and away from moisture and heat sources.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC/HPLC)	≥ 98.0%
Density (at 20°C)	~1.00 g/mL
Refractive Index (n20D)	~1.420

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.