Description

Lupitidine CAS NO 83903-06-4 is a selective histamine H2-receptor antagonist, a compound of significant interest in pharmaceutical research and development. Its primary value lies in its potent and specific mechanism of action, which makes it a crucial intermediate for investigating gastric acid secretion and related therapeutic pathways. This high-purity chemical is essential for researchers and manufacturers in the pharmaceutical industry, particularly those focused on developing or producing novel gastrointestinal agents and receptor-targeted drugs.

Application

• Key intermediate in the synthesis of advanced pharmaceutical actives targeting histamine H2-receptors.
• Critical reference standard for analytical method development and quality control in pharmaceutical manufacturing.
• Active pharmaceutical ingredient (API) research for novel anti-ulcer and gastroprotective drug candidates.
• Biochemical tool for pharmacological studies and receptor binding assays in academic and industrial R&D.
• Starting material for the preparation of deuterated or other isotopically labeled analogs for metabolic studies.
• Component in non-clinical research for evaluating the efficacy and safety of gastrointestinal therapeutics.

Basic Information

Product Name	Lupitidine
CAS No.	83903-06-4
Molecular Formula	C19H24N4O3S
Molecular Weight	388.48 g/mol
Synonyms	Lupitidine; SK&F 93479; 2-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]-N-(2-((diaminomethylene)amino)-4-thiazolylmethyl)acetamide; 2-({[2-(Carbamimidamido)-1,3-thiazol-4-yl]methyl}sulfanyl)-N-{[2-(carbamimidamido)-1,3-thiazol-4-yl]methyl}acetamide; SKF-93479; SKF 93479
EINECS	Contact for details

Quality Control

Our Lupitidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to current industry best practices, and specifications can be aligned with customer-specific requirements for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.