Description

1H-Indole-3-Carbonyl Chloride, 2-Chloro- (9Ci) is a highly reactive and versatile indole derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in its ability to introduce the 2-chloroindole-3-carbonyl moiety, a key structural motif for modulating biological activity and material properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who are developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Material Science Research: Employed in the creation of specialized polymers, liquid crystals, and organic electronic materials due to its indole core structure.
• Bioconjugation & Probe Development: Acts as a reactive handle for labeling biomolecules or creating fluorescent probes and diagnostic agents in life sciences.
• Academic & R&D Laboratories: Serves as a fundamental reagent for methodological studies in heterocyclic and medicinal chemistry.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses producing complex, high-value organic molecules for clients.

Basic Information

Item	Detail
Product Name	1H-Indole-3-Carbonyl Chloride, 2-Chloro- (9Ci)
CAS No.	83894-17-1
Molecular Formula	C9H5Cl2NO
Molecular Weight	214.05 g/mol
Synonyms	2-Chloro-1H-indole-3-carbonyl chloride; 2-Chloroindole-3-carbonyl chloride; 2-Chloro-1H-indole-3-carboxylic acid chloride; 2-Chloroindole-3-carboxylic acid chloride; 83894-17-1; 2-Chloro-1H-indole-3-carbonylchloride; 2-Chloroindol-3-carbonylchlorid
EINECS	Contact for details

Quality Control

Every batch of 1H-Indole-3-Carbonyl Chloride, 2-Chloro- (9Ci) is produced and tested under a strict quality management system. We ensure high purity and consistency through advanced analytical techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its reactive acid chloride nature and hygroscopic properties, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Keep away from strong bases, oxidizers, and alcohols.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.