Description

Methyl 3Alpha-[(Ethoxycarbonyl)Oxy]-7Alpha,12Alpha-Dihydroxycholan-24-Oate is a high-purity, semi-synthetic bile acid derivative, specifically a methyl ester of a modified cholic acid. This compound is of significant value as a critical pharmaceutical intermediate and a versatile research chemical for probing metabolic pathways. It is primarily needed by manufacturers and research institutions in the pharmaceutical, biochemical research, and fine chemical synthesis sectors.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel therapeutic agents targeting liver and metabolic disorders.
• Biochemical Research: Used as a reference standard or probe in studies of bile acid metabolism, receptor binding, and transporter function.
• Fine Chemical Synthesis: Serves as a chiral precursor for the preparation of more complex steroid-based molecules and specialty chemicals.
• Metabolite Standard: Essential for analytical method development and validation in clinical and preclinical bioanalysis.
• Academic & Industrial R&D: Facilitates discovery research in medicinal chemistry and molecular biology related to sterol pathways.

Basic Information

Item	Detail
Product Name	Methyl 3Alpha-[(Ethoxycarbonyl)Oxy]-7Alpha,12Alpha-Dihydroxycholan-24-Oate
CAS No.	83861-28-3
Molecular Formula	C₂₈H₄₆O₈
Molecular Weight	510.67 g/mol
Synonyms	Methyl 3α-[(ethoxycarbonyl)oxy]-7α,12α-dihydroxy-5β-cholan-24-oate; 3α-(Ethoxycarbonyloxy)-7α,12α-dihydroxy-5β-cholan-24-oic Acid Methyl Ester; Taurochenodeoxycholic Acid Methyl Ester Derivative; Cholic Acid Derivative Methyl Ester; 7α,12α-Dihydroxy-3α-[(ethoxycarbonyl)oxy]cholan-24-oic Acid Methyl Ester; 5β-Cholan-24-oic Acid, 3α-[(ethoxycarbonyl)oxy]-7α,12α-dihydroxy-, Methyl Ester; Methyl 3α-(ethoxycarbonyloxy)-7α,12α-dihydroxycholanate
EINECS	Contact for details

Quality Control

Our Methyl 3Alpha-[(Ethoxycarbonyl)Oxy]-7Alpha,12Alpha-Dihydroxycholan-24-Oate is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting full specifications are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.