Description

Ketanserin Tartrate is a high-purity, selective serotonin receptor antagonist (5-HT2A) with significant research and pharmaceutical applications. This compound is valued for its precise pharmacological activity, making it a critical reference standard and intermediate in drug discovery and development. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of active pharmaceutical ingredients (APIs) for cardiovascular and neurological research.

Application

• Pharmaceutical Reference Standard: Used as a certified standard for analytical method development, validation, and quality control in API and finished drug product manufacturing.
• Biochemical Research: A key tool for studying serotonin (5-HT) receptor mechanisms, signal transduction pathways, and receptor-ligand interactions in vitro.
• Drug Discovery & Development: Serves as a lead compound or intermediate in the synthesis of novel therapeutic agents targeting hypertension, vasospasm, and related cardiovascular conditions.
• Preclinical Studies: Employed in animal models to investigate the pharmacological effects of 5-HT2A receptor blockade on blood pressure and vascular tone.
• Academic Research: Utilized in university and institutional labs for fundamental neuropharmacology and cardiovascular research projects.

Basic Information

Product Name	Ketanserin Tartrate
CAS No.	83846-83-7
Molecular Formula	C26H28FN3O9
Molecular Weight	545.52 g/mol
Synonyms	Ketanserin L-(+)-Tartrate; 3-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-2,4(1H,3H)-quinazolinedione Tartrate; R 41 468; R-41468; Suress; Sufrexal; Ketensin
EINECS	Contact for details

Quality Control

Our Ketanserin Tartrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and stringent control of residual solvents and related substances. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research and development grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.