Description

1,2-Benzenedicarbonyl Difluoride, 4,5-Difluoro- (9Ci) is a highly reactive, multi-fluorinated aromatic building block of significant interest in advanced organic synthesis. Its value lies in its ability to act as a versatile precursor for introducing the 4,5-difluorophthaloyl moiety into complex molecular architectures, enabling precise tuning of electronic and steric properties. This compound is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients, as well as in materials science for creating specialty polymers and liquid crystals.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex drug molecules, particularly in the synthesis of kinase inhibitors and other targeted therapies where the difluorinated aromatic ring system is critical for bioactivity and metabolic stability.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where fluorination enhances lipophilicity and environmental persistence.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for the production of high-performance polymers, such as polyimides and polyamides, imparting improved thermal stability, chemical resistance, and unique optical properties.
• Liquid Crystal Manufacturing: Employed in the synthesis of fluorinated liquid crystal compounds for advanced display technologies (LCDs), where it helps optimize dielectric anisotropy and viscosity.
• Organic Electronics: Acts as a precursor for electron-transport materials and semiconductors used in OLEDs and organic photovoltaics.
• Chemical Research & Development: A valuable reagent for exploring new fluorination methodologies and creating novel fluorinated aromatic compounds in academic and industrial R&D laboratories.

Basic Information

Item	Details
Product Name	1,2-Benzenedicarbonyl Difluoride, 4,5-Difluoro- (9Ci)
CAS No.	83684-75-7
Molecular Formula	C8H2F4O2
Molecular Weight	206.10 g/mol
Synonyms	4,5-Difluorophthaloyl Difluoride; 4,5-Difluoroisophthaloyl Difluoride; 1,2-Bis(fluorocarbonyl)-4,5-difluorobenzene; 4,5-Difluorobenzene-1,2-dicarbonyl Difluoride; Isophthaloyl Difluoride, 4,5-difluoro-; 4,5-Difluoro-1,2-benzenedicarboxylic Acid Difluoride; 4,5-DFPD
EINECS	Contact for details

Quality Control

Our 1,2-Benzenedicarbonyl Difluoride, 4,5-Difluoro- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and process chemistry. Specifications are verified by techniques including HPLC, GC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when prolonged exposure is anticipated to prevent hydrolysis. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.