Description

(2E)-3-(2-Methylphenyl)Acryloyl Chloride is a high-purity, reactive acid chloride derivative of ortho-methylcinnamic acid. This compound is a critical building block in advanced organic synthesis, valued for its ability to introduce the (2-methylphenyl)acryloyl moiety into target molecules. It is primarily used by pharmaceutical and agrochemical research and development teams for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, including kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for specialty polymers with tailored properties.
• Liquid Crystal & OLED Materials: Serves as a building block for advanced electronic materials requiring specific aromatic structures.
• Peptide Mimetics & Bioconjugation: Utilized for acylating amines in the creation of peptide analogs or for labeling biomolecules.
• Dye & Pigment Manufacturing: Intermediate in the production of complex organic dyes and colorants.

Basic Information

Product Name	(2E)-3-(2-Methylphenyl)Acryloyl Chloride
CAS No.	83612-52-6
Molecular Formula	C10H9ClO
Molecular Weight	180.63 g/mol
Synonyms	(E)-3-(2-Methylphenyl)prop-2-enoyl chloride; 2-Methylcinnamoyl chloride; (E)-2-Methylcinnamoyl chloride; trans-2-Methylcinnamoyl chloride; o-Methylcinnamoyl chloride; 3-(2-Methylphenyl)-2-propenoyl chloride; (2E)-3-(2-Methylphenyl)-2-propenoyl chloride
EINECS	Contact for details

Quality Control

Every batch of our (2E)-3-(2-Methylphenyl)Acryloyl Chloride is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high standards required for research and commercial synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Keep away from strong bases, oxidizers, and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.