Description

Cyclopropanecarbonyl Chloride, 2-Chloro-1-Methyl- (9Ci) is a specialized organic building block featuring a reactive acid chloride functional group on a substituted cyclopropane ring. This compound matters as a key synthetic intermediate for introducing the sterically constrained and pharmacologically interesting cyclopropane moiety into more complex molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides with unique modes of action.
• Material Science Research: Employed to create monomers and polymers with specific mechanical or optical properties derived from the cyclopropane structure.
• Chemical Biology Probes: Serves as a reagent for modifying proteins or other biomolecules to study biological pathways and interactions.
• Catalyst & Ligand Development: Used to construct complex, chiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	Cyclopropanecarbonyl Chloride, 2-Chloro-1-Methyl- (9Ci)
CAS No.	83553-05-3
Molecular Formula	C5H6Cl2O
Molecular Weight	152.99 g/mol
Synonyms	2-Chloro-1-methylcyclopropanecarbonyl chloride; 1-Methyl-2-chlorocyclopropanecarboxylic acid chloride; (2-Chloro-1-methylcyclopropyl)carbonyl chloride; 2-Chloro-1-methylcyclopropanecarboxylic acid chloride; 2-Chloro-1-methylcyclopropanecarboxyl chloride
EINECS	Contact for details

Quality Control

Our Cyclopropanecarbonyl Chloride, 2-Chloro-1-Methyl- (9Ci) is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopy (NMR, IR), to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic and moisture-sensitive nature, containers should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.