Description

1-α-D-Arabinofuranosyl-2-Nitro-1H-Imidazole is a specialized nucleoside analog of significant interest in pharmaceutical research and development. This compound serves as a critical building block and intermediate for the synthesis of novel therapeutic agents, particularly in the field of antiviral and anticancer drug discovery. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the development of nucleoside-based pharmaceuticals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of experimental antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate nucleoside metabolism and related pathways.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Antiviral Agent Development: Investigated for its potential activity against viral polymerases and as a prodrug candidate.
• Labeled Compound Synthesis: Can be used to prepare radiolabeled or stable isotope-labeled versions for pharmacokinetic and metabolic tracing studies.
• Academic Research: Employed in university and institutional labs for fundamental studies in organic chemistry and chemical biology.

Basic Information

Item	Details
Product Name	1-α-D-Arabinofuranosyl-2-Nitro-1H-Imidazole
CAS No.	83416-40-4
Molecular Formula	C8H11N3O6
Molecular Weight	245.19 g/mol
Synonyms	2-Nitro-1-(β-D-arabinofuranosyl)imidazole; 1-(β-D-Arabinofuranosyl)-2-nitroimidazole; 2-Nitro-1-β-D-arabinofuranosylimidazole; Arabinofuranosyl-2-nitroimidazole; 2-Nitroimidazole arabinoside; 1-β-D-Arabinofuranosyl-2-nitro-1H-imidazole; NSC 382198
EINECS	Contact for details

Quality Control

Our 1-α-D-Arabinofuranosyl-2-Nitro-1H-Imidazole is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for research and development applications. All materials are accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.