Description

1H-Pyrazole-3-Carbonyl Chloride, 5-(1,1-Dimethylethyl)- (9Ci) is a high-purity, reactive chemical intermediate characterized by its pyrazole core and acid chloride functionality. This compound matters for its role as a critical building block in the synthesis of more complex molecules, enabling the introduction of the pyrazole-3-carboxamide moiety. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients, such as kinase inhibitors and fungicides.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Building block for developing advanced fungicides, herbicides, and plant growth regulators.
• Material Science Research: Used in the creation of novel polymers, ligands, and metal-organic frameworks (MOFs) with specialized properties.
• Chemical Biology & Proteomics: Employed as a derivatization agent or linker for probing enzyme activity and protein interactions.
• Custom Synthesis & Contract Manufacturing: Serves as a starting material for custom synthesis projects and scale-up production for clients.
• Academic & Industrial R&D: Fundamental reagent for methodological development and exploring new chemical reactions in heterocyclic chemistry.

Basic Information

Product Name	1H-Pyrazole-3-Carbonyl Chloride, 5-(1,1-Dimethylethyl)- (9Ci)
CAS No.	83405-72-5
Molecular Formula	C8H11ClN2O
Molecular Weight	186.64 g/mol
Synonyms	5-tert-Butyl-1H-pyrazole-3-carbonyl chloride; 5-(tert-Butyl)-1H-pyrazole-3-carbonyl chloride; 5-tert-Butylpyrazole-3-carbonyl chloride; 3-Carbonyl chloride-5-tert-butyl-1H-pyrazole; 5-(1,1-Dimethylethyl)-1H-pyrazole-3-carbonyl chloride; tert-Butylpyrazole-3-carbonyl chloride; 5-tert-Butyl-1H-pyrazole-3-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 1H-Pyrazole-3-Carbonyl Chloride, 5-(1,1-Dimethylethyl)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, it should be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage. Recommended storage temperature is 2-8°C. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.