Description

Adenosine 6-n-Phosphoramidate CAS NO 83305-95-7 is a chemically modified nucleotide analog, serving as a key intermediate in the synthesis of more complex nucleoside derivatives and prodrugs. Its value lies in its role as a versatile building block for pharmaceutical research, enabling the development of novel therapeutic agents targeting various cellular pathways. This high-purity biochemical is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors, particularly those focused on antiviral, anticancer, and metabolic disorder drug discovery.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of nucleoside-based prodrugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate nucleotide metabolism and signaling pathways.
• Antiviral Drug Development: Serves as a building block for creating analogs that may interfere with viral replication mechanisms.
• Anticancer Agent Synthesis: Employed in the research and development of nucleotide analogs designed to disrupt cancer cell proliferation.
• Prodrug Design: Utilized to create masked phosphate derivatives that improve the bioavailability and targeting of nucleoside drugs.
• Life Science Reagents: Incorporated into high-value reagent kits for molecular biology and diagnostic assay development.

Basic Information

Product Name	Adenosine 6-n-Phosphoramidate
CAS No.	83305-95-7
Molecular Formula	C10H15N6O7P
Molecular Weight	362.24 g/mol
Synonyms	6-Phosphoramidoadenosine; Adenosine 6'-phosphoramidate; 6'-O-Phosphoramidoadenosine; Adenosine 6'-O-phosphoramidate; 6'-Deoxy-6'-phosphoramidoadenosine; 9-β-D-Ribofuranosyladenine 6-n-phosphoramidate; AMPA (Adenosine Monophosphoramidate); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our Adenosine 6-n-Phosphoramidate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.