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1 β-Arabinofuranosylcytosine 5'-Diphosphate-1,2-Diolein CAS NO 83214-12-4


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CAS No.:83214-12-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1 β-Arabinofuranosylcytosine 5'-Diphosphate-1,2-Diolein is a complex, high-purity nucleotide-lipid conjugate, a critical biochemical building block for advanced research and development. This compound matters for its role as a specialized precursor in the synthesis of novel lipid-modified nucleotides and for studying membrane-associated enzymatic processes. It is primarily needed by pharmaceutical R&D teams, academic biochemistry laboratories, and biotechnology companies focused on nucleotide therapeutics, prodrug development, and signal transduction research.

Application

  • Biochemical Research: A key substrate for studying phospholipase and related enzyme kinetics and mechanisms.
  • Nucleotide Prodrug Development: Serves as a sophisticated precursor in the design of lipophilic nucleotide analogs to enhance cellular uptake and bioavailability.
  • Lipidomics & Metabolomics: Used as a reference standard or an analytical tool in the study of complex lipid-nucleotide interactions within biological systems.
  • Signal Transduction Studies: Investigates the role of lipid-modified nucleotides in intracellular signaling pathways.
  • Pharmaceutical R&D: Employed in early-stage discovery for novel antiviral or anticancer agents where nucleotide delivery is a challenge.
  • Enzyme Assay Development: Acts as a specific substrate for the development and validation of high-throughput screening assays targeting nucleotide-metabolizing enzymes.

Basic Information

Product Name 1 β-Arabinofuranosylcytosine 5'-Diphosphate-1,2-Diolein
CAS No. 83214-12-4
Molecular Formula C47H84N3O16P2
Molecular Weight 1008.13 g/mol
Synonyms 1-β-D-Arabinofuranosylcytosine 5'-(1,2-Dioleoyl-sn-glycerol Diphosphate); Cytarabine 5'-Diphosphate-1,2-Diolein; Ara-CDP-Diolein; 1,2-Dioleoyl-sn-glycerol Cytarabine Diphosphate; Lipid-modified Cytarabine Diphosphate; Nucleotide-Diacylglycerol Conjugate; Cytosine Arabinoside Diphosphate Diolein
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Quality Control

Our 1 β-Arabinofuranosylcytosine 5'-Diphosphate-1,2-Diolein is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation and NMR for structural verification, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) with full chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated under an inert atmosphere. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item Specification
Appearance White to off-white solid or film
Identification (HPLC) Conforms to reference standard
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95%
Water Content (KF) ≤ 2.0%
Solubility Soluble in chloroform, methanol; slightly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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