Description

(4-n-(2-Chloroethyl)-n-Methylaminobenzyl)Amide Guanosine-5'-Triphosphate is a chemically modified nucleotide analog, specifically a derivative of GTP (Guanosine-5'-triphosphate). This compound is of significant interest in biochemical and pharmacological research due to its potential as a mechanism-based inhibitor or a targeted molecular probe. It is primarily utilized by research institutions and pharmaceutical companies engaged in advanced studies of nucleotide metabolism, enzyme kinetics, and targeted drug delivery systems.

Application

• Biochemical Research: Used as a specialized substrate or inhibitor in enzymatic studies, particularly those involving GTP-binding proteins (G-proteins) and kinases.
• Pharmacological Probe Development: Serves as a key intermediate or active component in the synthesis of targeted therapeutic agents, especially in oncology research.
• Molecular Biology: Potential application in studying signal transduction pathways and cellular regulation mechanisms where GTP analogs are required.
• Drug Discovery: Employed in high-throughput screening assays to identify modulators of specific nucleotide-dependent biological targets.
• Academic Research: Utilized in universities and research institutes for fundamental studies on nucleotide chemistry and bio-conjugation strategies.

Basic Information

Product Name	(4-n-(2-Chloroethyl)-n-Methylaminobenzyl)Amide Guanosine-5'-Triphosphate
CAS No.	83209-68-1
Molecular Formula	C20H27ClN7O13P3
Molecular Weight	701.82 g/mol
Synonyms	N-[4-[[(2-Chloroethyl)methylamino]methyl]benzoyl]-GTP; GTP Derivative 83209-68-1; Chloroethylamino Benzyl GTP Amide; Guanosine-5'-triphosphate, (4-[[(2-chloroethyl)methylamino]methyl]benzoyl)amide; Modified GTP Analog; Nucleotide Alkylating Agent; GTP-N-[4-((2-Chloroethyl)methylaminomethyl)benzoyl]amide
EINECS	Contact for details

Quality Control

Our (4-n-(2-Chloroethyl)-n-Methylaminobenzyl)Amide Guanosine-5'-Triphosphate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods (NMR, MS) for structural confirmation, to ensure high purity and batch-to-batch consistency suitable for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.