Description

Mifentidine CAS NO 83184-43-4 is a selective histamine H2-receptor antagonist. This compound is significant for its role as a key pharmaceutical intermediate in the research and development of therapeutic agents targeting gastric acid secretion. It is primarily needed by manufacturers and R&D facilities in the pharmaceutical and fine chemical industries engaged in producing novel gastrointestinal medications or conducting pharmacological studies.

Application

• Primary intermediate in the synthesis of advanced histamine H2-receptor antagonist drug candidates.
• Critical building block for research into new anti-ulcer and gastroprotective pharmaceutical formulations.
• Reference standard in analytical laboratories for quality control and method development in pharmaceutical manufacturing.
• Used in biochemical research to study the mechanism of action of H2-receptor blockers.
• Starting material for the preparation of derivatives for structure-activity relationship (SAR) studies.
• Key ingredient in non-clinical research and development pipelines for metabolic and digestive system disorders.

Basic Information

Product Name	Mifentidine
CAS No.	83184-43-4
Molecular Formula	C13H19N5O2S
Molecular Weight	309.39 g/mol
Synonyms	Mifentidine; 83184-43-4; 2-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]-N-(2-ethoxyethyl)acetamide; DA 4577; DA-4577; UNII-7X1U846K1W; 7X1U846K1W; Acetamide, 2-[[[2-[(aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]-N-(2-ethoxyethyl)-
EINECS	Contact for details

Quality Control

Our Mifentidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets high-purity standards suitable for pharmaceutical R&D. Certificates of Analysis (COA) documenting full specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single unknown impurity ≤0.5%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.