Description

Cyclopropanecarbonyl Chloride, 3-(Cyclobutylidenemethyl)-2,2-Dimethyl-, (1R-Cis)- (9Ci) is a specialized chiral building block of significant interest in advanced organic synthesis. This compound is valued for its unique bicyclic structure, which incorporates both cyclopropane and cyclobutene moieties, enabling the construction of complex, strained molecular architectures. It is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in creating novel core structures with potential biological activity.
• Agrochemical Synthesis: Used in the preparation of advanced pesticide and herbicide molecules, where its strained ring system can contribute to unique modes of action.
• Material Science Research: Serves as a precursor for specialty polymers or ligands with tailored steric and electronic properties.
• Asymmetric Catalysis: Potential use in the synthesis of chiral ligands or catalysts due to its defined stereochemistry at the (1R-Cis) position.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and exploring new chemical spaces in synthetic organic chemistry.

Basic Information

Item	Details
Product Name	Cyclopropanecarbonyl Chloride, 3-(Cyclobutylidenemethyl)-2,2-Dimethyl-, (1R-Cis)- (9Ci)
CAS No.	83148-93-0
Molecular Formula	C11H15ClO
Molecular Weight	198.69 g/mol
Synonyms	(1R-cis)-3-(Cyclobutylidenemethyl)-2,2-dimethylcyclopropanecarbonyl chloride; (1R,3S)-3-(Cyclobutylidenemethyl)-2,2-dimethylcyclopropanecarbonyl chloride; (1R,3S)-3-(Cyclobutylidenemethyl)-2,2-dimethylcyclopropanecarboxylic acid chloride; 3-(Cyclobutylidenemethyl)-2,2-dimethyl-(1R-cis)-cyclopropanecarbonyl chloride; Cyclopropanecarbonyl chloride, 3-(cyclobutylidenemethyl)-2,2-dimethyl-, (1R-cis)-
EINECS	Contact for details

Quality Control

Our Cyclopropanecarbonyl Chloride, 3-(Cyclobutylidenemethyl)-2,2-Dimethyl-, (1R-Cis)- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure high chemical and isomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, it should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage and opened only in a moisture-free environment. Recommended storage temperature: 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.