Description

6-Dimethylamino-2'-Deoxyguanosine is a modified nucleoside analog of deoxyguanosine, featuring a dimethylamino group at the 6-position of the purine ring. This specific modification makes it a valuable building block and research chemical in the development of oligonucleotides and nucleic acid probes. It is primarily utilized by researchers and manufacturers in the fields of pharmaceutical development, molecular biology, and diagnostic assay production. The compound is offered with a commitment to high purity and reliable supply for critical research and manufacturing applications.

Application

• Oligonucleotide Synthesis: As a modified phosphoramidite precursor for introducing specific functionalities into synthetic DNA and RNA strands.
• Biochemical Research: Used in studies investigating nucleic acid structure, function, and protein-nucleic acid interactions.
• Probe Development: Incorporation into labeled probes for fluorescence in situ hybridization (FISH) and other detection technologies.
• Antiviral/Anticancer Agent Research: Serves as a key intermediate or analog in the research and development of nucleoside-based therapeutics.
• Diagnostic Reagents: A component in the manufacture of specialized reagents for molecular diagnostics and genetic testing kits.
• Academic & Institutional Research: Supplied to universities and research institutes for fundamental studies in genetics and biochemistry.

Basic Information

Item	Details
Product Name	6-Dimethylamino-2'-Deoxyguanosine
CAS No.	83061-20-5
Molecular Formula	C12H18N6O4
Molecular Weight	310.31 g/mol
Synonyms	N2,N2-Dimethyl-2'-deoxyguanosine; 2'-Deoxy-N2,N2-dimethylguanosine; 6-(Dimethylamino)-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-2-one; 6-Dimethylaminodeoxyguanosine; dG(DM); DM-dG; N2,N2-Dimethyl-2'-deoxyguanosine
EINECS	Contact for details

Quality Control

Our 6-Dimethylamino-2'-Deoxyguanosine is produced and tested under a rigorous quality management system. Each batch is analyzed to ensure high chemical purity and identity, meeting the stringent requirements for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment. We support compliance with relevant research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.