Description

5-Mercurideoxycytidine Monophosphate is a specialized organomercury nucleotide analog, a key intermediate in biochemical research and pharmaceutical development. This compound is valued for its unique structure, which allows it to act as a substrate analog and potential inhibitor in enzymatic studies, particularly those involving nucleic acid metabolism. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies engaged in the development of novel therapeutic agents and advanced molecular biology tools.

Application

• Biochemical Research: Used as a substrate analog in enzymatic assays to study the mechanisms of DNA and RNA polymerases, nucleotidyltransferases, and other nucleic acid-modifying enzymes.
• Pharmaceutical Development: Serves as a critical intermediate in the synthesis of potential antiviral or anticancer nucleoside analogs, where its mercury moiety can be utilized for further functionalization.
• Molecular Probe Synthesis: Acts as a precursor for creating labeled or modified nucleotides used as probes in hybridization studies, diagnostic assays, and structural biology.
• Enzyme Inhibition Studies: Investigated for its potential to inhibit specific enzymes involved in nucleotide metabolism, aiding in target validation and drug discovery pathways.
• Academic Research: Employed in university and institutional labs for fundamental studies on nucleotide chemistry, metal-nucleotide interactions, and the toxicology of mercury-containing biomolecules.

Basic Information

Product Name	5-Mercurideoxycytidine Monophosphate
CAS No.	82872-24-0
Molecular Formula	C9H13HgN3O7P
Molecular Weight	515.79 g/mol
Synonyms	5-Hg-dCMP; 5-Mercuri-2'-deoxycytidine 5'-monophosphate; Mercury-deoxycytidine monophosphate; 5-(Mercurio)-2'-deoxycytidine-5'-phosphate; 2'-Deoxy-5-mercuricytidylic acid; dCMP-Hg; 5-Mercurated deoxycytidine monophosphate
EINECS	Contact for details

Quality Control

Every batch of 5-Mercurideoxycytidine Monophosphate is subjected to rigorous analytical testing to ensure identity, purity, and consistency. Our quality assurance protocols are designed to meet the exacting standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity (by HPLC), heavy metal content (specifically free mercury), and other critical parameters is provided with each shipment to guarantee traceability and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere when possible to ensure long-term stability. Keep the container sealed and allow it to reach room temperature before opening to minimize condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 3.0%
Heavy Metals (as Hg, total)	Specified on COA
Solubility	Soluble in aqueous buffers, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.