Description

3-Pyridinecarbonyl Chloride, 2,4-Dimethyl- (9Ci) is a versatile and reactive heterocyclic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its ability to introduce the 2,4-dimethylpyridine-3-carbonyl moiety, a key structural feature for modulating biological activity and material properties. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery for central nervous system (CNS) and metabolic disorders.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides where the pyridine core enhances efficacy and selectivity.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and metal complexation.
• Material Science Research: Employed in the development of functional polymers, liquid crystals, and organic electronic materials that require specific heterocyclic architectures.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	3-Pyridinecarbonyl Chloride, 2,4-Dimethyl- (9Ci)
CAS No.	82776-24-7
Molecular Formula	C8H8ClNO
Molecular Weight	169.61 g/mol
Synonyms	2,4-Dimethylnicotinoyl Chloride; 2,4-Dimethylpyridine-3-carbonyl Chloride; 3-Carbamoyl-2,4-dimethylpyridine Hydrochloride (precursor related); 2,4-Lutidine-3-carbonyl Chloride; 3-Pyridinecarbonyl chloride, 2,4-dimethyl-; 2,4-Dimethyl-3-pyridinecarbonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 3-Pyridinecarbonyl Chloride, 2,4-Dimethyl- (9Ci) is produced and tested under a strict quality management system. We ensure high purity and consistency suitable for demanding research and scale-up applications. Comprehensive analytical testing, including HPLC, GC, and NMR, is performed to verify identity, purity, and impurity profiles. A Certificate of Analysis (COA) documenting all test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.