Description

2-Cyclopropene-1-Carbonylchloride,2-Methyl-1-Phenyl-,(S)-(9Ci) is a chiral, highly reactive acid chloride derivative of a substituted cyclopropene. This compound matters as a specialized, high-value building block for the synthesis of complex, stereochemically defined molecules, particularly in pharmaceutical research and advanced material science. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders or anti-inflammatory pathways.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides with specific stereochemical requirements for enhanced efficacy.
• Ligand and Catalyst Precursor: Serves as a precursor for synthesizing chiral ligands and organometallic catalysts used in asymmetric synthesis.
• Polymer and Material Science: Employed to introduce strained cyclopropene moieties into polymer backbones or functional materials, imparting unique reactivity or physical properties.
• Chemical Biology Probes: Utilized in the creation of activity-based probes and molecular tags for studying biological processes due to its high and selective reactivity.
• Academic and Industrial R&D: A valuable reagent for methodological development in organic synthesis, particularly in cycloaddition and cross-coupling reactions.

Basic Information

Product Name	2-Cyclopropene-1-Carbonylchloride,2-Methyl-1-Phenyl-,(S)-(9Ci)
CAS No.	82555-75-7
Molecular Formula	C11H9ClO
Molecular Weight	192.64 g/mol
Synonyms	(S)-2-Methyl-1-phenylcycloprop-2-ene-1-carbonyl chloride; (1S)-2-Methyl-1-phenyl-2-cyclopropene-1-carbonyl chloride; (S)-1-Phenyl-2-methylcycloprop-2-ene-1-carbonyl chloride; 2-Cyclopropene-1-carbonyl chloride, 2-methyl-1-phenyl-, (S)-; (S)-2-Methyl-1-phenylcycloprop-2-enecarboxylic acid chloride; Chiral cyclopropenyl acid chloride; Phenylmethylcyclopropenecarbonyl chloride (S-enantiomer)
EINECS	Contact for details

Quality Control

Our production of 2-Cyclopropene-1-Carbonylchloride,2-Methyl-1-Phenyl-,(S)-(9Ci) adheres to stringent quality protocols suitable for research and process development applications. Every batch undergoes comprehensive analytical characterization, including chiral purity verification, to ensure consistency and reliability. Certificates of Analysis (COA) detailing assay, enantiomeric excess, and impurity profiles are provided with each shipment. We support compliance with relevant research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Due to its properties as a strong acid/organic solvent derivative, hygroscopic (moisture-sensitive), and highly volatile nature, store under an inert atmosphere (argon or nitrogen) at recommended temperatures of -20°C to 0°C for long-term stability. Keep the container in a cool, dry, and well-ventilated place, separate from bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.