Description

2-Cyclopropene-1-Carbonylchloride,2-Methyl-3-Phenyl-,(S)-(9Ci) is a chiral, optically active acid chloride derivative featuring a cyclopropene ring, a structure of significant interest in advanced synthetic chemistry. This compound matters as a high-value building block for the stereoselective synthesis of complex molecules, enabling the introduction of a strained, reactive cyclopropene moiety with defined stereochemistry. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients, as well as by academic institutions exploring new methodologies in asymmetric synthesis and materials science.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory agents.
• Agrochemical Research: Used in developing new generations of herbicides and pesticides with potentially enhanced activity and selectivity.
• Asymmetric Catalysis: Serves as a precursor for chiral ligands or catalysts used in enantioselective transformations.
• Material Science: Investigated as a monomer or cross-linking agent for creating polymers with unique mechanical or optical properties derived from the cyclopropene unit.
• Chemical Biology Probes: Utilized in the synthesis of activity-based probes or labeled compounds for studying biological processes due to the reactivity of the acid chloride and cyclopropene groups.
• Academic & Process Chemistry: Employed in methodological studies for ring-opening reactions, cycloadditions, and other transformations of strained ring systems.

Basic Information

Product Name	2-Cyclopropene-1-Carbonylchloride,2-Methyl-3-Phenyl-,(S)-(9Ci)
CAS No.	82555-71-3
Molecular Formula	C11H9ClO
Molecular Weight	192.64 g/mol
Synonyms	(S)-2-Methyl-3-phenylcycloprop-2-ene-1-carbonyl chloride; (1S)-2-Methyl-3-phenyl-2-cyclopropene-1-carbonyl chloride; (S)-2-Methyl-3-phenylcycloprop-2-enecarbonyl chloride; 2-Cyclopropene-1-carbonyl chloride, 2-methyl-3-phenyl-, (S)-; (S)-2-Methyl-3-phenylcycloprop-2-ene-1-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our production of 2-Cyclopropene-1-Carbonylchloride,2-Methyl-3-Phenyl-,(S)-(9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and purity for sensitive synthetic applications. All products undergo rigorous analytical testing, including chiral HPLC to confirm enantiomeric excess (ee) and NMR for structural verification. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent hydrolysis and degradation. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.