Description

2-Cyclopropene-1-Carbonyl Chloride, 2-(1,1-Dimethylethyl)- (9Ci) is a highly reactive and versatile acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the unique steric and electronic properties conferred by the cyclopropene and tert-butyl groups, enabling the construction of complex molecular architectures. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries seeking to introduce functionalized cyclopropane motifs.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting enzyme inhibition or requiring rigid, three-dimensional scaffolds.
• Agrochemical Synthesis: Used to create advanced active ingredients with enhanced biological activity and environmental stability for crop protection.
• Polymer & Materials Science: Serves as a monomer or cross-linking agent for developing specialty polymers with unique thermal or mechanical properties.
• Ligand & Catalyst Development: Employed in the preparation of sophisticated ligands for asymmetric catalysis and organometallic complexes.
• Chemical Biology Probes: Facilitates the labeling and study of biological systems through its reactive carbonyl chloride functionality.
• Academic & Industrial R&D: Fundamental reagent for methodological development and exploring new reaction pathways in organic chemistry.

Basic Information

Product Name	2-Cyclopropene-1-Carbonyl Chloride, 2-(1,1-Dimethylethyl)- (9Ci)
CAS No.	82495-40-7
Molecular Formula	C8H11ClO
Molecular Weight	158.62 g/mol
Synonyms	2-(tert-Butyl)cycloprop-2-ene-1-carbonyl chloride; 2-tert-Butylcycloprop-2-ene-1-carbonyl chloride; 2-(1,1-Dimethylethyl)-2-cyclopropene-1-carbonyl chloride; tert-Butylcyclopropenecarbonyl chloride; 2-tert-Butyl-2-cyclopropene-1-carbonyl chloride
EINECS	Contact for details

Quality Control

Our production of 2-Cyclopropene-1-Carbonyl Chloride adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for your critical syntheses. Each lot undergoes comprehensive analytical characterization, including NMR, GC, and HPLC analysis, to verify identity, purity, and the absence of critical impurities. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications. We operate under a cGMP-compliant quality management system for pharmaceutical-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Keep away from strong acids, bases, and oxidizing agents. For long-term storage, consider refrigeration at 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Purity (HPLC)	≥ 96.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.