Description

3,7,12,25-Tetrahydroxycholestan-24-One is a high-purity, multi-hydroxylated sterol derivative that serves as a critical intermediate in advanced organic synthesis. This compound is valued for its defined stereochemistry and functional groups, which make it a versatile building block for pharmaceutical research and fine chemical manufacturing. It is primarily utilized by research institutions and industrial laboratories focused on developing novel therapeutic agents, particularly in the fields of endocrinology and metabolic disease.

Application

• Pharmaceutical Intermediate: Key starting material or advanced intermediate in the synthesis of steroid-based active pharmaceutical ingredients (APIs) and novel drug candidates.
• Biochemical Research: Used as a reference standard or probe in metabolic pathway studies, enzyme inhibition assays, and receptor binding research.
• Fine Chemical Synthesis: Serves as a chiral precursor for the production of complex molecules in agrochemical and specialty chemical applications.
• Academic Research: Employed in university and institutional labs for methodological development in organic chemistry and sterol chemistry.

Basic Information

Product Name	3,7,12,25-Tetrahydroxycholestan-24-One
CAS No.	82280-61-3
Molecular Formula	C₂₇H₄₆O₅
Molecular Weight	450.66 g/mol
Synonyms	24-Keto-3,7,12,25-tetrahydroxycholestane; 3,7,12,25-Tetrahydroxy-24-oxocholestane; 24-Oxo-3,7,12,25-tetrahydroxycholestane; (24R)-3,7,12,25-Tetrahydroxycholestan-24-one; (24S)-3,7,12,25-Tetrahydroxycholestan-24-one; Tetrahydroxycholestanone; Cholestane-3,7,12,25-tetrol-24-one
EINECS	Contact for details

Quality Control

Our 3,7,12,25-Tetrahydroxycholestan-24-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by spectroscopic methods (IR, NMR), and residual solvent analysis to ensure it meets stringent research-grade specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.