Description

1-p-Tolyl-Cyclopentanecarbonyl Chloride is a specialized organic intermediate featuring a cyclopentane backbone substituted with a carbonyl chloride and a p-tolyl group. This molecular structure makes it a valuable building block for synthesizing more complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working on novel active ingredients. The compound's reactivity as an acid chloride enables its use in amide coupling and esterification reactions to create targeted compounds with specific biological or material properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders or metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of new pesticides, herbicides, or fungicides, where the cyclopentane and aromatic structure can contribute to biological activity.
• Material Science Research: Serves as a monomer or precursor for developing specialized polymers, liquid crystals, or organic electronic materials.
• Chemical Biology Probes: Employed in the creation of molecular probes and tags for studying biological processes and protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical reagent for fine chemical and CDMO (Contract Development and Manufacturing Organization) companies producing bespoke compounds for client projects.

Basic Information

Product Name	1-p-Tolyl-Cyclopentanecarbonyl Chloride
CAS No.	82278-33-9
Molecular Formula	C13H15ClO
Molecular Weight	222.71 g/mol
Synonyms	1-(4-Methylphenyl)cyclopentanecarbonyl chloride; 1-(p-Tolyl)cyclopentanecarbonyl chloride; 4-Methyl-α-(1-oxocyclopentyl)benzenecarbonyl chloride; Cyclopentanecarbonyl chloride, 1-(4-methylphenyl)-; 1-(4-Methylphenyl)cyclopentane-1-carbonyl chloride
EINECS	Contact for details

Quality Control

Our 1-p-Tolyl-Cyclopentanecarbonyl Chloride is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development applications. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting key parameters such as assay, identity, and impurity profiles. Our quality commitment supports compliance in cGMP and ISO environments where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.