Description

Inosine, [2,8-3H]- is a high-specific-activity, tritium-labeled nucleoside derivative, essential for advanced biochemical and pharmacological research. This radiolabeled compound is critical for conducting precise metabolic pathway tracing, receptor binding studies, and pharmacokinetic analysis. It is primarily utilized by research institutions, pharmaceutical R&D departments, and diagnostic developers requiring reliable tracers for nucleotide metabolism and drug discovery applications.

Application

• Biochemical Research: As a tracer for studying purine salvage pathways, nucleotide synthesis, and inosine metabolism in cell cultures and in vitro systems.
• Pharmacology & Drug Discovery: For radioligand binding assays to investigate interactions with adenosine receptors and other nucleoside-binding proteins.
• Metabolic Studies: In tracking the metabolic fate of inosine and its derivatives in various biological models.
• Diagnostic Development: Potential use in the research and development of diagnostic assays and imaging probes.
• Enzymology: As a substrate for enzymes such as purine nucleoside phosphorylase (PNP) in kinetic and mechanistic studies.

Basic Information

Product Name	Inosine, [2,8-3H]-
CAS No.	82252-19-5
Molecular Formula	C10H113H2N4O5
Molecular Weight	~269.2 g/mol (for labeled form)
Synonyms	9-β-D-Ribofuranosylhypoxanthine, [2,8-3H]-; Hypoxanthine riboside, tritiated; Tritiated Inosine; [2,8-3H]Inosine; Inosine (tritium labeled); 9-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-1H-purin-6-one, [2,8-3H]-
EINECS	Contact for details

Quality Control

Every batch of Inosine, [2,8-3H]- is manufactured and analyzed under strict quality protocols to ensure high radiochemical purity and specific activity. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing specific activity, radiochemical purity, solvent composition, and analytical methods (e.g., HPLC) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at or below -20°C in the original solvent as supplied. For long-term storage, keep at -70°C to -80°C. This product is light-sensitive (store away from light) and should be handled with appropriate safety measures for radioactive materials.

Specification

Item	Specification
Appearance	Clear, colorless to slightly yellow solution
Specific Activity	10-40 Ci/mmol (Contact for exact value)
Radiochemical Purity	≥ 95% (by HPLC)
Concentration	1 mCi/mL (Contact for exact value)
Solvent	Ethanol:Water (7:3) or similar
Identification	Co-chromatography with reference standard

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.