Description

Bz-Dmt-Deoxycytidine 2-Clph Diester Barium) is a specialized, high-purity chemical intermediate primarily used in advanced pharmaceutical synthesis and oligonucleotide research. This compound is critical for the development and production of nucleoside analogs and modified oligonucleotides, where precise chemical structure and purity are paramount. It serves as a key building block for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors, enabling the creation of novel therapeutic agents and diagnostic tools.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Oligonucleotide Synthesis: Used as a protected monomer in solid-phase synthesis for creating modified DNA/RNA strands for research and therapeutics.
• Prodrug Development: Employed in the design of prodrugs to enhance the bioavailability and targeting of active pharmaceutical ingredients.
• Bioconjugation: Serves as a linker or modifier in the conjugation of biomolecules for diagnostic and targeted drug delivery systems.
• Chemical Biology Research: A valuable tool for studying nucleic acid interactions, enzyme mechanisms, and cellular processes.
• API Manufacturing: Integrated into the production process of Active Pharmaceutical Ingredients (APIs) requiring specific nucleoside modifications.

Basic Information

Product Name	Bz-Dmt-Deoxycytidine 2-Clph Diester Barium)
CAS No.	82224-96-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Benzoyl-DMT-2'-Deoxycytidine 2-Chlorophenyl Diester Barium Salt; 5'-O-(4,4'-Dimethoxytrityl)-N4-benzoyl-2'-deoxycytidine 3'-(2-chlorophenyl phosphate) Barium Salt; Bz-dC(DMT) 2-Clph Barium Salt; Protected Deoxycytidine Phosphoramidite Precursor; Barium 5'-O-DMT-N-benzoyl-2'-deoxycytidine-3'-(2-chlorophenyl phosphate)
EINECS	Contact for details

Quality Control

Our Bz-Dmt-Deoxycytidine 2-Clph Diester Barium) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, essential for sensitive pharmaceutical applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, typically determined by advanced analytical techniques such as HPLC, NMR, and mass spectrometry. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions, ideally in a desiccator or with appropriate desiccant in the primary container. Handle and store under an inert atmosphere (e.g., nitrogen or argon) for long-term stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines
Barium Content	Conforms to theoretical value

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.